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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREBBP
All Species:
17.88
Human Site:
S709
Identified Species:
32.78
UniProt:
Q92793
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92793
NP_001073315.1
2442
265351
S709
R
P
P
N
G
P
L
S
L
P
V
N
R
M
Q
Chimpanzee
Pan troglodytes
XP_523285
2442
265358
S709
R
P
P
N
G
P
L
S
L
P
V
N
R
M
Q
Rhesus Macaque
Macaca mulatta
XP_001095225
2442
265320
S709
R
P
P
N
G
P
L
S
L
P
V
N
R
M
Q
Dog
Lupus familis
XP_851777
2404
260682
P671
R
P
P
N
G
P
M
P
L
P
V
N
R
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
P708
R
P
P
N
G
P
L
P
L
P
V
N
R
M
Q
Rat
Rattus norvegicus
NP_596872
2444
265618
S708
R
P
P
N
G
P
L
S
L
P
V
N
R
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414964
2447
266615
T707
N
G
P
M
S
M
T
T
V
P
I
S
R
M
Q
Frog
Xenopus laevis
NP_001088637
2428
264402
V704
G
P
I
S
M
S
T
V
P
T
M
N
R
M
Q
Zebra Danio
Brachydanio rerio
NP_001082924
2111
234059
P582
A
P
L
R
A
T
P
P
P
N
T
T
A
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
V1060
A
G
V
A
G
G
V
V
L
P
Q
Q
Q
Q
Q
Honey Bee
Apis mellifera
XP_001122031
2606
284119
S828
G
V
G
T
V
P
P
S
R
P
V
G
T
V
T
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
N527
L
A
N
L
I
G
V
N
G
N
S
N
G
S
A
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
V905
D
K
R
M
G
N
L
V
A
Y
A
R
K
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
93.9
N.A.
94.8
95.8
N.A.
N.A.
88
76
61.5
N.A.
36.5
42.7
30.5
38.5
Protein Similarity:
100
99.9
99.6
95.5
N.A.
96.4
97.2
N.A.
N.A.
92
83.3
68.8
N.A.
46.7
54.7
43.9
50.9
P-Site Identity:
100
100
100
80
N.A.
93.3
93.3
N.A.
N.A.
33.3
33.3
6.6
N.A.
26.6
26.6
6.6
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
N.A.
60
46.6
6.6
N.A.
40
33.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
8
8
0
0
0
8
0
8
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
16
8
0
62
16
0
0
8
0
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
8
0
8
8
0
0
47
0
54
0
0
0
0
0
0
% L
% Met:
0
0
0
16
8
8
8
0
0
0
8
0
0
47
0
% M
% Asn:
8
0
8
47
0
8
0
8
0
16
0
62
0
0
0
% N
% Pro:
0
62
54
0
0
54
16
24
16
70
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
8
8
8
70
% Q
% Arg:
47
0
8
8
0
0
0
0
8
0
0
8
62
0
0
% R
% Ser:
0
0
0
8
8
8
0
39
0
0
8
8
0
8
8
% S
% Thr:
0
0
0
8
0
8
16
8
0
8
8
8
8
0
8
% T
% Val:
0
8
8
0
8
0
16
24
8
0
54
0
0
31
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _